Syllabus - Bio-process Technology (CM-702 (B))

Introduction to Bio-Chemical Engineering

Aspects of microbiology, cell theory structure of microbial cells, classification of microorganism, Essential chemicals of life lipids, Sugars and Polysaccharides, RNA and DNA, Amino acids and proteins.

Metabolism and Energetic

Assimilatory and dissimilatory process, metabolic mechanism of the cells; Biochemical Kinetics: Simple enzyme kinetics with one or two substrates, modulation and regulation of enzymatic activity, enzyme reactions in heterogeneous systems.

Growth cycle, phases for Batch cultivation, mathematical modeling of batch growth, roducts synthesis Kinetics, overall kinetics and thermal death kinetics of cells and spores.

Unit Operations in Biochemical Process

Agitation and aeration, gas liquid mass transfer, determination of oxygen transfer rates, determination of Kga and KLa scaling of mass transfer equipment, heat balance and heat transfer correlation for biochemical systems, sterilization, filtration and drying.

Design and Analysis of Bio-Reactors

Classification and characterization of different bioreactors, batch and continuous reactors, tubular, CSTR and tower reactors, aerobic and anaerobic fermentation-process, design and operation of typical aerobic and anaerobic fermentation processes, manufacture of microbial products e.g. antibiotics alcohol/ wine etc; use of immobilized enzyme and whole cells for industrial processes.